Role Of NONI In Influenza
Influenza (commonly known as the flu) is one of the most feared and deadly infectious diseases. The severity of the infection and the duration of the illness, however, depend on several factors, including:
Resistance of the respiratory tract to oxidative stress associated with influenza infection, as well as its ability to mount a local immune/inflammatory response and its ability to manufacture and secrete antibodies
Resistance of the respiratory tract to oxidative stress associated with influenza infection, as well as its ability to mount a local immune/inflammatory response and its ability to manufacture and secrete antibodies
Level of immunity against that particular strain of influenza
Overall health of the person’s immune system
Antioxidant status
Overall nutritional and general health status
Role of Noni
There are two main types of flu viruses: influenza A and influenza B. The most serious and deadly flu outbreaks are caused by influenza A because of its ability to genetically shift into new forms against which no person has developed immunity. Infection with the flu begins with exposure of the upper respiratory tract to the virus. In infected cells, viral replication occurs 4 to 6 hours after infection, after which time the infected cell bursts, spreading the virus to nearby cells. The cycle then repeats, infecting more and more cells each time. This accounts for the incubation period for the flu, which ranges from about 18 to 72 hours, depending on the strain and the effectiveness of the body’s immune response. The more virulent the strain, and/or the weaker the host's immunity, the sooner the cycle of cell death and viral spread produces noticeable symptoms. People who have weak immune systems, such as the elderly, sick people, or young children, can therefore be quickly overwhelmed by strong strains of the virus.
Noni is a great immune enhancer. Noni stimulates the release of various cytokines mediator of the immune system of our body like
Interleukin
Interferon – gamma
Nitric oxide
Tumour necrosis factor
Natural killer cells
At the same time that this nonspecific response is occurring, the body is creating specific antibodies to recognize and destroy that particular strain of flu virus in the future. The body’s immune system relies on T-cells and B-cells, which are coded to identify specific antigens (invaders) and stimulate a more effective and rapid immune response in the event of future infection. In the case of the influenza virus, antibodies against the flu are detected in the second week after primary infection. These antibodies will help protect against similar strains of the flu in the future. New strains, such as those created by genetic shifting, retain their full power.
Antioxidant property of Noni
Endogenous antioxidants and role of Noni
Our body has evolved with endogenous defense mechanisms to protect against free radical induced cell damage. Glutathione peroxidase, catalase, and Superoxide dismutases are three primary antioxidant enzymes in our body, which involved in direct elimination of free radicals or reactive oxygen species from our body. They require micronutrient such as selenium, iron, copper, zinc, and manganese as cofactors for their formation and optimum catalytic and effective antioxidant activity. Noni contain all the trace minerals that help for optimum catalytic activity of those three important antioxidant enzymes for an effective antioxidant defense mechanism.
Glutathione, ascorbic acid, alpha-tocopherol, beta-carotene, bilirubin, selenium, dihydrolipoic acid, reduced CoQ10, melatonin, uric acid etc., as a whole play a homoeostatic or protective role against ROS produced during normal cellular metabolism and after active oxidation insult. Noni contains all the above phyto chemicals and vitamins in abundant quantity. Glutathione (GSH) is the most significant component which directly quenches Reactive Oxygen Species (ROS) such as lipid peroxides and plays major role in xenobiotic metabolism. Glutathione is a tripeptide made up of the amino acids gamma-glutamic acid, cysteine, and glycine. Noni contain all those glutathione making amino acids in abundant number. Thus Noni increases the body’s glutathione level. Noni stimulates more melatonin secretion from the pineal body. It also maintains ascorbate (vitamin C) and alpha-tocopherol (vitamin E), in their reduced form, which also exert an antioxidant effect by quenching free radicals.
Exogenous antioxidants: Contribution from Noni
A number of other dietary antioxidants known as phytonutrients or phytochemicals that are being increasingly appreciated for their antioxidant activity. One example is flavonoids which are a group of polyphenolic compounds. They are responsible for the different brilliant colors such as blue, scarlet, and orange. Noni contain 150 above phytochemicals including all flavonoids. Flavonoids exhibit several biological effects such as antitumoural, anti-ischaemic, anti-allergic, anti-hepatotoxic, anti-ulcerative, and anti inflammatory activities. Noni is rich with many flavonoids.
Noni has antiviral, antimicrobial, anticancer, and immune-enhancing effects. Noni may stimulate macrophages, which in turn may help induce cell-mediated immunity. Noni has been shown to inhibit bacteria and viruses and stimulate the immune system.
Ten Rules of Success
This is an article taken from Trump University.
Top Ten Rules of Success
by Donald J. Trump
If you've heard me speak, you may have noticed I emphasize several things repeatedly - never give up is one, being passionate is another, keeping focused is up there, and keeping your momentum runs a close fourth. I've learned those things from experience.
1. Never give up! Do not settle for remaining in your comfort zone. Remaining complacent is a good way to get nowhere.
2. Be passionate! If you love what you're doing, it will never seem like work.
3. Be focused! Ask yourself: What should I be thinking about right now? Shut out interference. In this age of multitasking, this is a valuable technique to acquire.
4. Keep your momentum! Listen, apply and move forward. Do not procrastinate.
5. See yourself as victorious! That will focus you in the right direction.
6. Be tenacious! Being stubborn can work wonders.
7. Be lucky! The old saying, "The harder I work, the luckier I get" is absolutely right on.
8. Believe in yourself! If you don't, no one else will either. Think of yourself as a one-man or one-woman army.
9. Ask yourself: What am I pretending not to see? There may be some great opportunities right around you, even if things aren't looking so great. Great adversity can turn into great victory.
10. Look at the solution, not the problem. And never give up! Never never never give up. This thought deserves to be said (and remembered and applied) many times. It's that important.
Good luck!
Top Ten Rules of Success
by Donald J. Trump
If you've heard me speak, you may have noticed I emphasize several things repeatedly - never give up is one, being passionate is another, keeping focused is up there, and keeping your momentum runs a close fourth. I've learned those things from experience.
Here's the complete top 10 list I give when I speak at colleges:
1. Never give up! Do not settle for remaining in your comfort zone. Remaining complacent is a good way to get nowhere.
2. Be passionate! If you love what you're doing, it will never seem like work.
3. Be focused! Ask yourself: What should I be thinking about right now? Shut out interference. In this age of multitasking, this is a valuable technique to acquire.
4. Keep your momentum! Listen, apply and move forward. Do not procrastinate.
5. See yourself as victorious! That will focus you in the right direction.
6. Be tenacious! Being stubborn can work wonders.
7. Be lucky! The old saying, "The harder I work, the luckier I get" is absolutely right on.
8. Believe in yourself! If you don't, no one else will either. Think of yourself as a one-man or one-woman army.
9. Ask yourself: What am I pretending not to see? There may be some great opportunities right around you, even if things aren't looking so great. Great adversity can turn into great victory.
10. Look at the solution, not the problem. And never give up! Never never never give up. This thought deserves to be said (and remembered and applied) many times. It's that important.
Good luck!
Male And Female Infertility
ROLE OF NONI IN MALE AND FEMALE INFERTILIT
Infertility is not a "woman's" problem. It is a medical problem of the male or female reproductive system. In about one third of cases, the cause is traced to the woman, another third of cases are traced to the man. The rest are caused by unknown factors or a physiological incompatibility.
Infertility is not only a physical condition--it is an emotional and social condition with accompanying feelings and issues. The infertile couple needs support and consideration from the treatment team, friends, family, and each other.
What is the cause of male infertility and female infertility?
Roughly one-third of infertility cases can be attributed to male factors and another one-third to factors that affect women. For the remaining infertile couples, infertility is caused by a combination of problems in both partners (about 13%) or is unexplained (about 10%).
The most common causes of male infertility include azoospermia (no sperm cells are produced) and oligospermia (few sperm cells are produced). Sometimes, sperm cells are malformed or they die before they can reach the egg.
The most common cause of female infertility is an ovulation disorder. Other causes of female infertility include blocked fallopian tubes, polycystic ovary syndrome (PCOS) and endometriosis. Repeated miscarriages may be caused by congenital anomalies (birth defects) involving the structure of the uterus and uterine fibroids.
Role Of Noni in case of infertility
If there is any base line cause of any pathological derangement for the infertility then it should be treated first. But if the infertility is due to some other factors like endocrinological (hormonal) imbalance or environmental factors then noni may help. Noni acts like a powerful immune modulator hence help in keeping your endocrine system in a well balance condition. So may help in case of sterility.
In case low semen production Noni may help to improve this condition. If the infertility is due to the underline cause of high increase of free radical's damage then noni may help to improve this condition as it has high power anti oxidant properties.
Noni is able to affect so many systems is through its ability to promote new cellular growth and to repair damaged cells. Everything in our body is made up of cells. An accumulation of damaged cells could result in a damaged organ or system. There are several ways that Noni can help rebuild the body's overall cellular growth. To begin, Noni is a powerful antioxidant. Much has been written in recent years about cellular damage resulting from free radicals.
Free radicals occur when the chains of important biochemicals in the body are broken with a resultant unpaired electron remaining. This occurs because of oxidization in the body. The "radicals" of these broken chains then move around the body as free radicals, causing damage to other cells. When a cell in hit by a free radical, the cell may become more permeable and leaky. The mitochondria may actually be compromised, or DNA might be damaged. Many scenarios result in a "sick cell". In order to combat the potential effects of free radicals, the body needs to first prevent oxidization (with an anti – oxidant), and next, it needs something to rebuild the already damaged cells. Studies show that NONI can help do both. In addition to the antioxidant activity in Noni, Dr. Ralph Heinicke, Ph.D., has pinpointed constituents in Noni that he believes are responsible for the Juice's ability to promote cellular growth. These are parts of his postulated xeronine system, which consists of proxeronine, proxeroninease, and xeronine.
Why Noni works for so many conditions
The natural integrity of noni is only part of the reason for its effectiveness. There are two additional reasons contribution to noni's effectiveness for a broad range of conditions:
1. Unique Combinations of Substances
For a fruit, which sit he most digestively efficient of all foods, noni has an impressive combination of ingredients. It has a rich complement of vitamins and minerals; including A, B vitamins (including the rare B-12), C, E, Iron, calcium, sodium, potassium, zinc and several trace minerals. It also has 17 of 20 amino acids. Terpenes, fungicides, adaptogens, glycosides, polysaccharides and other unique ingredients that even in small amounts can have significant physiological effects can be found in Noni. Studies show that NONI stimulates the immune system, regulates proper cell function, increases the ability of cells to absorb and utilize nutrients, inhibits tumor growth, and regenerates damaged cells. Probably the most unique ingredient is an alkaloid called xeronine.Xeronine has several important functions including regulating the many proteins in the body, activating inactive enzymes and improving cellular function. Noni also contains a substance called proxeronine, which can be stored in the liver according to Dr. Ralph Heinecke. Proxeronine, in turn, can be used to make xeronine, as needed. Noni has very good serotonin binding ability. Serotonin is important for several functions, including sleep quality, hunger, sexual behaviour, temperature regulation; and several personality disorders\ including depression, anxiety, irritability and attention deficit conditions. Scopoletin, another important ingredient in noni, is known for its anti inflammatory, anti histaminic, improved circulation, anti-asthmatic, anti bacterial and several additional important effects.It works like a food and acts like a medicine or herb without the side effects.
2. Synergy of its Substances
The many known, and even some of the unknown substances, come together in a way that support the needs of many of our internal systems, concurrently. As the word synergy implies, these substances work far better in combination than they do separately. Many of the ingredients in noni are found in varying amounts in other foods or herbs. There seems to be no known food or herb with either the rich list of substances or the high amounts of key substances all put together in one super food. Noni aids the body's natural healing abilities.
So here I can suggest you both continue noni for a longer period just for a trial basis as because till yet it has not been established all the therapeutic effects of noni in all diseases. But you must keep in your mind that it is not a medicine for any diseases but a best nutritional supplements which contain all the micronutrients that our all cell needs and our body needs. The deficiency of those micronutrients is the cause of many diseases.
Infertility is not a "woman's" problem. It is a medical problem of the male or female reproductive system. In about one third of cases, the cause is traced to the woman, another third of cases are traced to the man. The rest are caused by unknown factors or a physiological incompatibility.
Infertility is not only a physical condition--it is an emotional and social condition with accompanying feelings and issues. The infertile couple needs support and consideration from the treatment team, friends, family, and each other.
What is the cause of male infertility and female infertility?
Roughly one-third of infertility cases can be attributed to male factors and another one-third to factors that affect women. For the remaining infertile couples, infertility is caused by a combination of problems in both partners (about 13%) or is unexplained (about 10%).
The most common causes of male infertility include azoospermia (no sperm cells are produced) and oligospermia (few sperm cells are produced). Sometimes, sperm cells are malformed or they die before they can reach the egg.
The most common cause of female infertility is an ovulation disorder. Other causes of female infertility include blocked fallopian tubes, polycystic ovary syndrome (PCOS) and endometriosis. Repeated miscarriages may be caused by congenital anomalies (birth defects) involving the structure of the uterus and uterine fibroids.
Role Of Noni in case of infertility
If there is any base line cause of any pathological derangement for the infertility then it should be treated first. But if the infertility is due to some other factors like endocrinological (hormonal) imbalance or environmental factors then noni may help. Noni acts like a powerful immune modulator hence help in keeping your endocrine system in a well balance condition. So may help in case of sterility.
In case low semen production Noni may help to improve this condition. If the infertility is due to the underline cause of high increase of free radical's damage then noni may help to improve this condition as it has high power anti oxidant properties.
Noni is able to affect so many systems is through its ability to promote new cellular growth and to repair damaged cells. Everything in our body is made up of cells. An accumulation of damaged cells could result in a damaged organ or system. There are several ways that Noni can help rebuild the body's overall cellular growth. To begin, Noni is a powerful antioxidant. Much has been written in recent years about cellular damage resulting from free radicals.
Free radicals occur when the chains of important biochemicals in the body are broken with a resultant unpaired electron remaining. This occurs because of oxidization in the body. The "radicals" of these broken chains then move around the body as free radicals, causing damage to other cells. When a cell in hit by a free radical, the cell may become more permeable and leaky. The mitochondria may actually be compromised, or DNA might be damaged. Many scenarios result in a "sick cell". In order to combat the potential effects of free radicals, the body needs to first prevent oxidization (with an anti – oxidant), and next, it needs something to rebuild the already damaged cells. Studies show that NONI can help do both. In addition to the antioxidant activity in Noni, Dr. Ralph Heinicke, Ph.D., has pinpointed constituents in Noni that he believes are responsible for the Juice's ability to promote cellular growth. These are parts of his postulated xeronine system, which consists of proxeronine, proxeroninease, and xeronine.
Why Noni works for so many conditions
The natural integrity of noni is only part of the reason for its effectiveness. There are two additional reasons contribution to noni's effectiveness for a broad range of conditions:
1. Unique Combinations of Substances
For a fruit, which sit he most digestively efficient of all foods, noni has an impressive combination of ingredients. It has a rich complement of vitamins and minerals; including A, B vitamins (including the rare B-12), C, E, Iron, calcium, sodium, potassium, zinc and several trace minerals. It also has 17 of 20 amino acids. Terpenes, fungicides, adaptogens, glycosides, polysaccharides and other unique ingredients that even in small amounts can have significant physiological effects can be found in Noni. Studies show that NONI stimulates the immune system, regulates proper cell function, increases the ability of cells to absorb and utilize nutrients, inhibits tumor growth, and regenerates damaged cells. Probably the most unique ingredient is an alkaloid called xeronine.Xeronine has several important functions including regulating the many proteins in the body, activating inactive enzymes and improving cellular function. Noni also contains a substance called proxeronine, which can be stored in the liver according to Dr. Ralph Heinecke. Proxeronine, in turn, can be used to make xeronine, as needed. Noni has very good serotonin binding ability. Serotonin is important for several functions, including sleep quality, hunger, sexual behaviour, temperature regulation; and several personality disorders\ including depression, anxiety, irritability and attention deficit conditions. Scopoletin, another important ingredient in noni, is known for its anti inflammatory, anti histaminic, improved circulation, anti-asthmatic, anti bacterial and several additional important effects.It works like a food and acts like a medicine or herb without the side effects.
2. Synergy of its Substances
The many known, and even some of the unknown substances, come together in a way that support the needs of many of our internal systems, concurrently. As the word synergy implies, these substances work far better in combination than they do separately. Many of the ingredients in noni are found in varying amounts in other foods or herbs. There seems to be no known food or herb with either the rich list of substances or the high amounts of key substances all put together in one super food. Noni aids the body's natural healing abilities.
So here I can suggest you both continue noni for a longer period just for a trial basis as because till yet it has not been established all the therapeutic effects of noni in all diseases. But you must keep in your mind that it is not a medicine for any diseases but a best nutritional supplements which contain all the micronutrients that our all cell needs and our body needs. The deficiency of those micronutrients is the cause of many diseases.
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