Plant Components – Benefits & Mechanism
The Noni plant contains a number of components which may be responsible for its purported benefits.
Xeronines (proxeronine & proxeroninase)
Alkaloid that interacts with structurally abnormal proteins to convert them into their proper conformation; thought to be a critical normal metabolic coregulator; aids in hypertension, menstrual cramps, arthritis, ulcers, musculoskeletal injuries, indigestion, depression, and addictions
Scopoletin
Dilates vasculature, anti-bacterial, anti-fungal, anti-inflammatory, analgesic, histamine-inhibiting, serotonin modulator; aids in arthritis, allergies, migraines, depression, hypertension
Anthraquinones (damnacanthal)
Antiseptic and anti-bacterial effects
Polysaccharides (noni-ppt, galactose, arabinose, rhamnose, glucuronic acid)
Immunostimulatory, immunomodulatory, anti-tumor effects; may play a role in the cancer-fighting benefits of noni
Glycosides (rutin, asperulosidic acid)
Free radical scavengers, inhibition of UVB-induced activator protein-1 activity; role in cancer-fighting effects
Amino acids and essential fatty acids
Building blocks for protein, fats, and oils; necessary for healthy skin, maintenance of normal nervous system, cardiovascular system, and cellular function
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