Heart Diseases (Cardiac Diseases)

Heart Attact

Heart attack is the number-one cause of death in whole world. Our fastidious life style, rich diet habits, physical inactivity, stress full mental condition are the predisposing factors of various cardiac problems and heart attacks. The high rise of cholesterol in our blood is one of the causes of many cardiac problems and the heart attacks. The oily fatty food, ghee, fried foods has become a habit in our daily routine diet. It all causes the rise of cholesterol in our blood and plays the main role in generating various heart diseases like coronary artery diseases, ischemic heart diseases, atherosclerotic plaques in artery, unstable angina pain etc.

Cholesterol is of two types – HDL (high density lipoprotein) cholesterol and LDL (low density lipoprotein) cholesterol. Among them HDL cholesterol is good for our body. But LDL cholesterol is named as bad cholesterol and this is the one which is the route cause of coronary artery diseases, angina pain, and atherosclerosis of artery etc. Native LDL cholesterol is good. In fact it is essential for building good cell membrane, others cell parts, and many different hormones that our body needs. Problems begin when native LDL cholesterols are oxidized by the free radicals in our body and make them the harmful cholesterol. The high environmental pollutions, our stressful life style, a good nutrients depleted diet are the main causes of over production of free radicals in our body. Those free radicals play the main role to oxidize LDL cholesterol and make it harmful to our body.

The inner layer of our artery is called the endothelium which is an extremely sensitive lining that is vulnerable to even slightest irritation. Oxidized cholesterol, excessive free radicals causes the oxidative stress that injures the endothelium. Our body has a defense system designed to protect this endothelium of the artery. In the events of injury, our body responses by sending WBC (mainly monocytes) in an attempt to eliminate the harmful oxidized LDL cholesterol. Here the defense team of monocytes starts gobbling up the enemy in an attempt to minimize the irritation to the endothelium. If this response process is successful, the problem is over and the lining of the artery will be repaired. But this is not what usually happens. Monocytes continue to gather the delinquent oxidized LDL cholesterol, but they don’t let any out. Hence the monocytes gets crammed so full of oxidized LDL cholesterol(fat) that it becomes a foam cell, looks like a ball of fat. This foam cells then attach itself to the lining of the artery and eventually forms the initial defect of hardening of the arteries which is called fatty streak. The fatty streak is an inflammatory lesion. This leads to form a plaque. It is the initial step in the process called atherosclerosis. The atherosclerotic plaque goes on increasing in size and consequently makes the artery narrow inside to pass the blood flow. The entire process is a vicious cycle. Not only there is build up plaque, but there is also thickening of artery. Normally the layer of endothelium function well by releasing an important product called nitrous oxide (NO). During this inflammatory response, however, the appropriate release of nitrous oxide is blocked from the endothelium, causing the endothelium to function poorly. This in turn causes the platelets of blood to adhere to the plaque and the artery around the plaque to go into spasm. About 50% of heart attacks are the rapture of one of these plaques and the clot that forms around a ruptured plaque. A situation such as this causes acute and abrupt total closure of this artery, which blocks the blood flow to that part of the heart. Oxidative stress may also cause the break down of these plaques, which eventually leads to their rupture.

Arteries can keep narrowing to the point that they become occluded. These patients have usually had symptoms of chest pain that is called unstable angina.

So to neutralize the notorious activity of those free radicals to convert the native LDL cholesterol to harmful LDL cholesterol it is required some powerful antioxidants. Those antioxidants not only neutralize the effect of free radicals on the vessels cells but also to other cells.

Noni have the powerful antioxidant properties that help to neutralize the free radicals role of oxidation of the native LDL cholesterol to harmful LDL cholesterol and thus protects the arterial endothelial lining from injury and future developing atheromatous plaque. The main antioxidants are vitamins A, E and C, beta-carotene, glutathione, bioflavonoid, selenium, zinc, CoQ10 (ubiquinone), and various phyto-chemicals. Noni is rich with Vita A, Beta carotene, Vita E, C, glutathione, bioflavonoid, selenium, zinc, and many more essential phytochemicals. Melatonin, a hormone produced by the pineal gland, is also a potent antioxidant. Noni helps to stimulate more melatonin release from the pineal gland.

Why Noni works as powerful antioxidants.

There are two reasons:

Unique Combinations of Substances
For a fruit, Noni has an impressive combination of ingredients. It has a rich complement of vitamins and minerals; including A, B vitamins (including the rare B-12), C, E, Iron, calcium, sodium, potassium, zinc and several trace minerals. It also has 17 out of total 20 amino acids including all the essential amino acid. Terpenes, fungicides, adaptogens, glycosides, polysaccharides and other unique ingredients that even in small amounts can have significant physiological effects can be found in Noni.

Synergy of its Substances

The many known, and even some of the unknown substances, come together in a way that support the needs of many of our internal systems, concurrently. As the word synergy implies, these substances work far better in combination than they do separately. Many of the ingredients in Noni are found in varying amounts in other foods or herbs. There seems to be no known food or herb with either the rich list of substances or the high amounts of key substances all put together in one super food. Noni aids the body’s natural healing abilities.

Noni & nitric oxide – its role in preventing arterial cells damage
Normally the layer of endothelium function well by releasing an important product called nitrous oxide (NO). During this inflammatory response of forming the plaques, however, the appropriate release of nitrous oxide is blocked from the endothelium, causing the endothelium to function poorly. Noni helps to proper production of nitrous oxide in our body and thus helps the endothelium to functions smoothly.

Noni promotes the cellular growth
In addition to the antioxidant activity in Noni, Dr. Ralph Heinicke, has pinpointed one constituent in Noni that he believes are responsible for the Juice’s ability to promote cellular growth. These are parts of his postulated xeronine system, which consists of proxeronine, proxeroninase, and xeronine.

The xeronine theory, which is based on much of Dr. Heinicke’s work, postulates that once in the body, proxeronine travels to specific parts of cells, such as the mitochondria, microsomes, Golgiapparatus, reticuloendothelium, electron transport system, within the cell, these components communicate with each other (intracellular) and with other cells (intercellular). This communication between cells may work according to the theories of several Nobel Prize winning doctors.